KMID : 0361720050160010023
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Korean Journal of perinatology 2005 Volume.16 No. 1 p.23 ~ p.30
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Association between Hematologic Abnormalities and Severity in Neonate with NEC.
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Kim Seok-Young
Park Bum-Chul Lee Cho-Ae Cho Young-Ah Kim Se-Hyun Lee Kyu-Hyung
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Abstract
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Objective: The purpose of this study is to evaluate the association between hematologic abnormalities and severity in neonate with NEC.
Method: A retrospective chart review was established of 69 premature infants with a diagnosis of NEC who had been admitted to Pochon CHA University neonatal intensive care unit between Jan 2001 and Jun 2004. Infants were divided into three groups according to Bell¡¯s criteria. The association between perinatal and clinical manifestation, hematologic abnormalities and severity in neonate with NEC was evaluated.
Results: Nadir platelet counts, neutropenia, I:T ratio, CRP and base excess were associated with severity of NEC, but coagulation disturbances (DIC) were not significantly correlated with severity of NEC.
Conclusion: These preliminary results may be helpful to predict the severity and to improve the outcome in neonate with NEC.
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KEYWORD
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NEC, DIC
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